List of COVID-19 Vaccine Efficacy in Indonesia, Which is the Highest?

[3 bucks new rv rate]

   

List of COVID-19 Vaccine Efficacy in Indonesia, Which is the Highest?
Ardela Nabila
Fri, 30 July 2021 2.23 PM
 

 

 

VIVA – One of the Government's efforts to reduce the number of cases of COVID-19 infection is to hold a vaccination program. According to the Ministry of Health (Kemenkes), there are six types of vaccines that will be used in Indonesia. In addition to the type, the efficacy of the available vaccines also varies.

The six types of vaccines are Sinovac, AstraZeneca, Sinopharm, Moderna, Pfizer, and Novavax. Although each vaccine has its own differences, the Ministry of Health ensures that the vaccine provided is a vaccine that is safe and effective.

However, although it is stated that there are six types of vaccines, the Food and Drug Supervisory Agency (BPOM) has just issued an Emergency Use Authorization (EUA) for five types of vaccines. Currently, the Novavax vaccine is still in the process of obtaining a permit for use.

To find out more, see the efficacy of the COVID-19 vaccine used in Indonesia below, as summarized from the official BPOM website.

 

Sinovac
BPOM first issued a policy for the Sinovac vaccine in early 2021. In its development, this vaccine has gone through various stages of clinical trials, one of which was carried out in Indonesia.

The results of the analysis of the efficacy of the vaccine produced by Sinovac Biotech during clinical trials in Bandung showed an efficacy of 65.3 percent. Meanwhile, reports of efficacy in other clinical trial countries, namely Turkey and Brazil, were 91.25 percent and 78 percent, respectively.

 

AstraZeneca
The AstraZeneca vaccine is a vaccine developed by Oxford University. This vaccine has been included in the list approved by the World Health Organization (WHO). Apart from Indonesia, AstraZeneca is also used in the UK, European Union, Malaysia, and other countries.

Based on data from clinical trials of administering two doses of AstraZeneca vaccine at intervals of 4-12 weeks to 23,745 subjects, this vaccine was declared safe and showed 62.10 percent efficacy.

 

Sinopharm
Manufactured by the Beijing Bio-Institute Biological Products Co, the Sinopharm vaccine is already undergoing phase three clinical trials in the United Arab Emirates and other countries with a total of 42,000 test subjects.

The test results show that this vaccine has an efficacy of 78.02 percent. Meanwhile, the results of immunogenicity after 14 days of injection of the second dose showed a neutralization seropositive rate of 99.52 percent in adults and 100 percent in the elderly.

 

Moderna
The vaccine, which received EUA permission in early July, is included in the list of one of the vaccines also used in Indonesia. Phase three clinical trials conducted in November 2020 showed that this vaccine had an efficacy of 94.1 percent in the age group 18 to under 65 years.

Meanwhile, in the age group of 65 years and over, the efficacy of the Moderna vaccine is 84.4 percent. These results were obtained from observations starting on the 14th day after injection.

 

Pfizer
Pfizer is a vaccine that recently received EUA clearance from BPOM. Produced by Pfizer and BioNTech, this vaccine can be given to people aged 12 years and over. Immunogenicity data show that this vaccine has been shown to produce a good immune response.

Based on phase three clinical trial data, the Pfizer vaccine efficacy at the age of 16 years and over showed a success of 95.5 percent. Meanwhile, in adolescents aged 12-15 years and over, the efficacy is 100 percent.

 

link  :  https://id.yahoo.com/berita/daftar-efikasi-vaksin-covid-19-072348493.html

 

[3 bucks new rv rate]

 

Differences between AstraZeneca and Sinovac Vaccines, from Content, Efficacy, to Side Effects
Mon, August 2, 2021 3:45 PM

 

Liputan6.com, Jakarta You may need to understand the difference between AstraZeneca and Sinovac vaccines. The reason is, the two types of vaccines are the most widely used in Indonesia. Even though they both have the same goal, you still have to identify them in detail.

The AstraZeneca and Sinovac vaccines certainly have the same goal, namely to protect the body from exposure to the Corona virus. You need to pay attention to the content, dosage, side effects, technology used, to the efficacy. The difference between AstraZeneca and Sinovac vaccines can be seen from the content to their efficacy.

AstraZeneca and Sinovac vaccines have been declared to meet international standards by WHO, both in the manufacturing process, safety, and efficacy. So, of course you don't need to be picky about vaccines anymore. The sooner everyone gets the vaccine, the sooner this pandemic will end.

Here Liputan6.com summarizes from various sources, Monday (2/8/2021) about the differences between the AstraZeneca vaccine and the Sinovac vaccine.

 Origin, Content, and Age of Recipient

The content of these two types of vaccines is the most basic difference that you need to know. The AstraZeneca vaccine was developed by the AstraZeneca company and the University of Oxford, England, while the Sinovac vaccine was developed by the Chinese pharmaceutical company Sinovac.

The Sinovac vaccine uses an inactivated virus platform, while the AstraZeneca vaccine uses an adenovirus vector. The basic ingredient of the Sinovac vaccine is the corona virus (SARS-CoV-2) that has been killed. Meanwhile, the basic ingredients of the AstraZeneca vaccine are vector adenoviruses or genetically modified viruses.

The difference between AstraZeneca and Sinovac vaccines can also be seen from the age of the recipients. AstraZeneca vaccine can be given to people aged under 65 years, ie 18-64 years. While the Sinovac vaccine can be given to people aged 18-59 years. However, in Indonesia BPOM allows vaccines to be given at the age of over 60 years.

 

Vaccine Administration Range

As is well known, the COVID-19 vaccine is given in two doses. The WHO recommended dose is the same for both, which is 0.5 ml for the first and second dose injections. The difference between AstraZeneca and Sinovac vaccines can also be seen from the schedule for administering the first and second vaccines. Sinovac vaccine is given in 2-4 weeks, while AstraZeneca vaccine is given in 8-12 weeks.

Difference Between AstraZeneca and Sinovac Vaccines

 

 

Efficacy

The next difference between AstraZeneca and Sinovac vaccines is in efficacy. Reporting from KlikDokter, efficacy is the percentage decrease in the incidence of disease in the group of people who are vaccinated. So, efficacy indicates the ability of a vaccine but in a research context.

The vaccine efficacy required by WHO is more than 50%. Both vaccines have more than 50% efficacy as required by WHO. Sinovac vaccine has 56-65% efficacy, while AstraZeneca vaccine has 62-75% efficacy. Thus, both types of vaccines are confirmed to be effective in protecting the body from exposure to the Corona virus.

 

Side effects

The side effects felt after the AstraZeneca and Sinovac vaccines are generally the same, namely pain at the injection site. However, sometimes there are also other symptoms such as fever, headache, muscle aches, to mild fatigue. Usually these symptoms will go away in just 1-2 days. If you feel severe symptoms, see a doctor immediately.

The Sinovac vaccine is made using a dead or inactivated virus. This makes the frequency of fever, headache, soreness in the recipient very low, which is around 2-4 percent. Evidently, the Sinovac vaccine can prevent severe disease, including preventing death.

Meanwhile, the AstraZeneca vaccine uses a viral vector. The mechanism is that the dead Corona virus is superimposed on a vector which is an attenuated adenovirus. This resulted in the frequency of fever, aches, headaches reaching 65 percent. However, in clinical trials, most vaccine side effects are mild to moderate and resolve within a few days. The AstraZeneca vaccine also has another advantage, namely that it can prevent the transmission of COVID-19.

 

link  : https://id.yahoo.com/berita/4-fakta-vaksin-moderna-di-123018332.html

[3 bucks new rv rate]

 

Minister of Health Explains about the News that the Efficacy of the Sinovac Vaccine Declines After 6 Months
Mon, August 2, 2021 3.31 PM

Liputan6.com, Jakarta Minister of Health (Menkes) Budi Gunadi Sadikin explained the news that the efficacy of the Sinovac Covid-19 vaccine would decrease after six months of injecting the second dose. Budi said that studies related to the efficacy of the vaccine will only be known after 3 clinical trials are completed.

"I must emphasize here, the vaccine efficacy or the vaccine retention period or the vaccine resistance period, will only be formally released after the completion of the final clinical trial report 3," said Budi in a press conference on the Presidential Secretariat Youtube, Monday (2/8/2021). ).

According to him, the 3rd clinical trial report is predicted to come out around the end of 2021. For this reason, there is no official explanation whether the vaccine's efficacy will decrease after six months of being injected into the community.

"At the end of this year we will know and after that we will definitely provide the steps for handling it," he said.

Regarding booster vaccines, Budi emphasized that currently only health workers will be prioritized. This is because they are in direct contact with Covid-19 patients, so they must receive maximum protection.

"I beg you very much, please don't be transferred to non-nakes. We must prioritize health workers," said Budi.

Nakes' Third Injection
Meanwhile, Indonesia received 4 million doses of the Covid-19 Moderna vaccine from the United States. A total of 1.5 million doses will be given to health workers as a booster or third injection.

"We give 1.5 million doses first to all health workers as a single shot, a third booster injection," said Budi.

 

link  :  https://id.yahoo.com/berita/menkes-jelaskan-soal-kabar-efikasi-083118025.html

[3 bucks new rv rate]

 

4 Facts about Moderna Vaccines in Indonesia for the Third Dose of Healthcare Workers
Ardela Nabila
Mon, 2 August 2021 7.30 PM

 

VIVA – Indonesia has just returned the arrival of the Moderna COVID-19 vaccine on Sunday, August 1, 2021. The Moderna vaccine in Indonesia as much as 3.5 doses was a gift from the United States.

Thus, the total number of vaccines that have been received in the country is 178,357,880 doses. Moderna itself is a vaccine developed with an mRNA platform and produced by Moderna TX., Inc. USA.

To find out more information related to the Moderna Indonesia vaccine, let's look at this series of facts about the vaccine that Indonesia had just received.

 

Already got EUA from BPOM
The Food and Drug Supervisory Agency (BPOM) has issued an Emergency Use Authorization (EUA) for the Moderna vaccine on July 2, 2021. Thus, making this vaccine included in the series of vaccines used in Indonesia together with Sinovac, AstraZeneca, and Sinopharm vaccines.

 

In addition, this vaccine is the first vaccine from the mRNA platform used in Indonesia.

Efficacy up to 94.1 percent
Based on data from a phase three clinical trial in November 2020, the Moderna vaccine has efficacy to prevent severe COVID-19 symptoms of up to 94.1 percent in the age group 18 to under 65 years. Meanwhile, in the age group 65 years and over, the efficacy is 86.4 percent.

The figures in the data were obtained through observations starting on the 14th day after the second dose was injected.

 

Used for the third dose injection
Indonesia is one of the countries in the world that will inject the third dose or booster to health workers and citizens. The decision to use the Moderna vaccine as a booster in Indonesia was taken by the Government after discussions with the Indonesian Technical Advisory Group of Immunization (ITAGI) and BPOM.

The third dose will be given regularly every year to health workers to strengthen their immunity.

Effective against Corona virus mutation
Quoted from the Yale Medicine website, the Moderna vaccine effectively provides protection against the Alpha and Beta variants of the Corona virus. However, at this time researchers are still trying to study the efficacy of the Moderna vaccine related to the Delta variant.

However, experts believe that this vaccine is just as effective as the Pfizer vaccine. Because, both are mRNA vaccines.

 

link  :  https://id.yahoo.com/berita/4-fakta-vaksin-moderna-di-123018332.html