coorslite21 Posted April 26, 2020 Report Share Posted April 26, 2020 (edited) As a rule people in the NE and Upper Midwest experience less sunlight during the winter months.....(shorter days, heavier coats)......Sunlight is known to be healthy.....along the northern borders of America people are generally healthier in the summer months......just how it is..... Spain is a warmer climate and they have been hit pretty hard.... They have initiated a study that should shed more "light" on this.....(sorry....just couldn't help myself)......for any interested who wish to look.. CLtt https://clinicaltrials.gov/ct2/show/NCT04334005 ps://www.coronaviruwww.nih.gov/coronavi . Find Studies About Studies Submit Studies Resources About Site Home Search Results Study Record Detail Save this study Vitamin D on Prevention and Treatment of COVID-19 (COVITD-19) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. ClinicalTrials.gov Identifier: NCT04334005 Recruitment Status : Not yet recruiting First Posted : April 3, 2020 Last Update Posted : April 7, 2020 See Contacts and Locations Sponsor: Universidad de Granada Information provided by (Responsible Party): Manuel Castillo Garzón, Universidad de Granada Study Details Tabular View No Results Posted Disclaimer How to Read a Study Record Study Description Go to Brief Summary: The new outbreak of the SARS-CoV-2 coronavirus is causing an important pandemic affecting a large number of people all-over the world. Vitamin D is a hormone precursor produced by our own body with the help of sunlight which has an important role on adaptive immunity and cellular differentiation, maturation and proliferation of several immune cells. Reduced levels of vitamin D in calves were positioned as the main cause of bovine coronavirus infection in the past. Therefore, it seems plausible that the use of vitamin D as a nutritional ergogenic aid could be a potential intervention to fight against COVID-19 infected patients which remain asymptomatic or which have non-severe and severe symptoms. This study aims to investigate whether the use of vitamin D as an immune modulator agent induces significant improvements of health status and outcomes in non-severe symptomatic patients infected with COVID-19 as well as preventing COVID-19 health deterioration. We hypothesize that vitamin D will significantly improve hard endpoints related to COVID-19 deleterious consequences compared with a usual care control group. Condition or disease Intervention/treatment Phase Patients Infected With COVID-19 Dietary Supplement: Vitamin D Not Applicable Study Design Go to Study Type : Interventional (Clinical Trial) Estimated Enrollment : 200 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Investigator, Outcomes Assessor) Primary Purpose: Treatment Official Title: Effect of Vitamin D Administration on Prevention and Treatment of Mild Forms of Suspected Covid-19 Estimated Study Start Date : April 10, 2020 Estimated Primary Completion Date : June 30, 2020 Estimated Study Completion Date : June 30, 2020 Resource links provided by the National Library of Medicine MedlinePlus related topics: Vitamin D Drug Information available for: Vitamin D U.S. FDA Resources Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Usual care Prescription of NSAIDs, ACE2 inhibitor, ARB or thiazolidinediones, according to clinician criteria, based on the current recommendations. Dietary Supplement: Vitamin D The intervention group will receive a single dose of 25000 UI of vitamin D supplement in addition to prescription of NSAIDs, ACE2 inhibitor, ARB or thiazolidinediones, according to clinician criteria, based on the current recommendations. Vitamin D supplementation will be taken in the morning together with a toast with olive oil to facilitate its absorption. Experimental: Intervention group 25000 UI of vitamin D supplement in addition to the above-mentioned drug recommendations. Dietary Supplement: Vitamin D The intervention group will receive a single dose of 25000 UI of vitamin D supplement in addition to prescription of NSAIDs, ACE2 inhibitor, ARB or thiazolidinediones, according to clinician criteria, based on the current recommendations. Vitamin D supplementation will be taken in the morning together with a toast with olive oil to facilitate its absorption. Outcome Measures Go to Primary Outcome Measures : Composite of cumulative death (i.e. mortality) for all causes and for specific causes. [ Time Frame: Through study completion, an average of 10 weeks ] Secondary Outcome Measures : Necessity of invasive assisted ventilation [ Time Frame: Through study completion, an average of 10 weeks ] Necessity of non-invasive assisted ventilation [ Time Frame: Through study completion, an average of 10 weeks ] Intensive care unit admission [ Time Frame: Through study completion, an average of 10 weeks ] Post-anesthesia care unit admission [ Time Frame: Through study completion, an average of 10 weeks ] Hospital admission [ Time Frame: Through study completion, an average of 10 weeks ] Medical consultation [ Time Frame: Through study completion, an average of 10 weeks ] Home care and isolation time [ Time Frame: Through study completion, an average of 10 weeks ] Bed rest time [ Time Frame: Through study completion, an average of 10 weeks ] symptoms' duration (i.e. cough, fever, nasal congestion, gastrointestinal symptoms, fatigue, anosmia, ageusia, diarrhea or alternative signs of COVID-19) [ Time Frame: Through study completion, an average of 10 weeks ] Subjective perception of recovery [ Time Frame: Through study completion, an average of 10 weeks ] It will be measure by questionnaire Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. Ages Eligible for Study: 40 Years to 70 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Non-severe symptomatic patients who present cough, fever, nasal congestion, gastrointestinal symptoms, fatigue, anosmia, ageusia or alternative signs of respiratory infections. Exclusion Criteria: Patients presenting severe respiratory and/or multisystemic symptoms compatible with advanced COVID-19 and intercurrent acute or severe chronic diseases (i.e. active cancer). Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04334005 Contacts Contact: Manuel J Castillo, MD, PhD +34 649440850 mcgarzon@ugr.es Locations Spain Universidad de Granada Granada, Andalucia, Spain, 18071 Contact: Manuel J. Castillo Garzón mcgarzon@ugr.es Medicine Faculty Granada, Spain, 18001 Contact: Proffesor Amaro Gahete, PhD student 697287022 ext +34 amarof@ugr.es Sponsors and Collaborators Universidad de Granada Investigators Principal Investigator: Manuel J Castillo, MD, PhD Universidad de Granada More Information Go to Responsible Party: Manuel Castillo Garzón, MD, PhD, Universidad de Granada ClinicalTrials.gov Identifier: NCT04334005 History of Changes Other Study ID Numbers: COVITD-19 First Posted: April 3, 2020 Key Record Dates Last Update Posted: April 7, 2020 Last Verified: April 2020 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Vitamin D Vitamins Micronutrients Nutrients Growth Substances Physiological Effects of Drugs Bone Density Conservation Agents TO TOP For Patients and Families For Researchers For Study Record Managers S. Department of Health and Human Services Edited April 26, 2020 by coorslite21 1 Quote Link to comment Share on other sites More sharing options...
umbertino Posted April 26, 2020 Report Share Posted April 26, 2020 Thanks for sharing, CL...Stay safe you and yours Quote Link to comment Share on other sites More sharing options...
yota691 Posted April 26, 2020 Report Share Posted April 26, 2020 2 9 1 Quote Link to comment Share on other sites More sharing options...
yota691 Posted April 26, 2020 Report Share Posted April 26, 2020 2 9 1 Quote Link to comment Share on other sites More sharing options...
8th ID Posted April 26, 2020 Report Share Posted April 26, 2020 @yota691, you made my day on those two! Thanks! 1 1 Quote Link to comment Share on other sites More sharing options...
bigwave Posted April 26, 2020 Report Share Posted April 26, 2020 13 hours ago, coorslite21 said: Spain is a warmer climate and they have been hit pretty hard.... CL - Did I miss something in your post? I did not search for other months due to time.... Spain Weather in January It's cold in January in most of Spain, but what did you expect? It's winter! Time to enjoy what winter in Spain can offer you (did you know you can ski in Spain?). https://www.tripsavvy.com/january-weather-in-spain-1644261 Madrid weather in February 12 12°C max day temperature 5 5 hours of sunshine per day 13 13 days with some rainfall 2 2°C min night temperature https://www.weather2travel.com/spain/madrid/february/ 1 Quote Link to comment Share on other sites More sharing options...
caddieman Posted April 26, 2020 Author Report Share Posted April 26, 2020 1 3 5 Quote Link to comment Share on other sites More sharing options...
MyLadiesDaddy Posted April 26, 2020 Report Share Posted April 26, 2020 M 1 hour ago, caddieman said: Son, you really have no idea what you're exposing about yourself 1 1 Quote Link to comment Share on other sites More sharing options...
caddieman Posted April 26, 2020 Author Report Share Posted April 26, 2020 13 minutes ago, ladyGrace'sDaddy said: M Son, you really have no idea what you're exposing about yourself Not your Son. But thanks for the advice. Stay Safe. 1 2 1 Quote Link to comment Share on other sites More sharing options...
MyLadiesDaddy Posted April 26, 2020 Report Share Posted April 26, 2020 1 hour ago, caddieman said: Not your Son. But thanks for the advice. Stay Safe. LOL. I wasn't always a Fine God fearing Catholic. In fact I was something of a scoundrel. So ya never know whose Daddy I am. 🤣🤣🤣😎😎😎 1 Quote Link to comment Share on other sites More sharing options...
caddieman Posted April 27, 2020 Author Report Share Posted April 27, 2020 Poison Control Centers Have Been Extra Busy Since President Trump Suggested Injecting Bleach Can Cure Coronavirus In the 18 hours after Trump’s widely condemned comments during the White House coronavirus task force briefing, the New York City Poison Control Center reported that it received nine calls about Lysol exposure, 10 calls about bleach exposure, and 11 about exposure to unnamed cleaners, according to WNBC in New York. That’s more than double the exposure calls the center received during the same period last year. https://www.vice.com/en_us/article/wxevan/poison-control-centers-have-been-extra-busy-since-president-trump-suggested-injecting-bleach-can-cure-coronavirus 1 1 2 1 Quote Link to comment Share on other sites More sharing options...
64jaguar Posted April 27, 2020 Report Share Posted April 27, 2020 On 4/27/2020 at 7:23 PM, caddieman said: Poison Control Centers Have Been Extra Busy Since President Trump Suggested Injecting Bleach Can Cure Coronavirus In the 18 hours after Trump’s widely condemned comments during the White House coronavirus task force briefing, the New York City Poison Control Center reported that it received nine calls about Lysol exposure, 10 calls about bleach exposure, and 11 about exposure to unnamed cleaners, according to WNBC in New York. That’s more than double the exposure calls the center received during the same period last year. https://www.vice.com/en_us/article/wxevan/poison-control-centers-have-been-extra-busy-since-president-trump-suggested-injecting-bleach-can-cure-coronavirus More FAKE news.... Hey Caddieman by any chance do you know JoeB? 2 2 Quote Link to comment Share on other sites More sharing options...
MyLadiesDaddy Posted April 28, 2020 Report Share Posted April 28, 2020 48 minutes ago, caddieman said: Poison Control Centers Have Been Extra Busy Since President Trump Suggested Injecting Bleach Can Cure Coronavirus And Hospitals all over America have been massively overwhelmed with Covid19 patients. As was stated earlier, idiot's who believe that President Trump made such a statement are why we have warning statements on everything. 1 1 2 Quote Link to comment Share on other sites More sharing options...
Sage449 Posted April 28, 2020 Report Share Posted April 28, 2020 Omgoodness I understood Trump to speculate maybe disinfectants could be a cure. He didn't say to use it. That's like saying use mold because it's penicillin and is a cure. We don't know what's in some of the chemicals contained inside injections. I surely don't understand what's in some of the pills OTC or vaccines, doesn't mean I'm going to run out and use them. How stupid are people today? Rhetorical. 5 2 Quote Link to comment Share on other sites More sharing options...
Muleslayer Posted April 30, 2020 Report Share Posted April 30, 2020 (edited) On 4/26/2020 at 1:15 PM, ladyGrace'sDaddy said: LOL. I wasn't always a Fine God fearing Catholic. In fact I was something of a scoundrel. So ya never know whose Daddy I am. 🤣🤣🤣😎😎😎 my squad mates asked me after liberty one weekend, what the hell were you and the parrot doing last night. i could not remember then 20 years later i met the parrot again and she told me that i was a father! i got a pick of her and my son! Edited April 30, 2020 by Muleslayer . 3 Quote Link to comment Share on other sites More sharing options...
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